Niacin improves microbiome and insulin resistance

The study shows the potential use of delayed-release nicotinic acid in improving the gut microbiota and insulin resistance, subsequently reducing the risk of prediabetes and diabetes. The modified niacin was able to reach the ileocolonic site intact and influencing microbiome by enhancing its α-diversity and abundance of Bacteroidetes. More research to come regarding gut flora–insulin resistance–diabetes axis.