• PCSK9 Gene Editing and the Logic of Prevention

    PCSK9 Gene Editing and the Logic of Prevention

    PCSK9 gene editing reaches beyond ordinary cholesterol treatment by changing the liver’s instructions for producing PCSK9. This reflective essay explains LDL receptor recycling, base editing, cumulative cholesterol exposure, and the promise of one-time therapy. It also examines the responsibility that comes with permanent biological change, balancing scientific innovation with the careful evidence, patient selection, and long-term monitoring that such powerful treatment requires before clinical use.

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