insulin resistance physiology

Insulin resistance changes how the body stores calories and shapes fat distribution patterns. The liver handles more glucose and fatty acids, which increases triglycerides and raises ApoB. Visceral fat grows faster, the waistline expands earlier, and the weight to waistline ratio worsens. These shifts influence cholesterol balance, blood pressure, and diabetes risk. Understanding these pathways helps patients identify early metabolic changes and prevent long term complications.