Mesenteric Vein Thrombosis During Testosterone Therapy

Can TRT contribute to small bowel obstruction? Rare reports connect excessive androgen exposure with erythrocytosis, abdominal thrombosis, and adult intussusception. However, most cases involved supraphysiologic anabolic-steroid use rather than monitored testosterone therapy. This review separates established evidence from proposed mechanisms. It also explains hematocrit monitoring and abdominal warning signs requiring immediate medical evaluation. The distinction matters for patients and clinicians considering treatment safety.